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SSO2 Therapy in STEMI to Reduce Infarct Size

Steven Yakubov, Andreas Schäfer, Richard Schatz et al

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Natriuretic Peptides in Chronic Heart Failure

Hans-Peter Brunner-La Rocca, Sandra Sanders-van Wijk,

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Biomarkers in Routine Heart Failure Clinical Care

Sunil K Nadar, Muhammad Mujtaba Shaikh,

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Practical Applications for Single Pill Combinations in the Cardiovascular…

Ferdinando Iellamo, Karl Werdan, Krzysztof Narkiewicz, et al

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Nitrates as a Treatment of Acute Heart Failure

Mohammad S Alzahri, Anita Rohra , W Frank Peacock,

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Biomarker Guided Therapy in Chronic Heart Failure

Hans-Peter Brunner-La Rocca, Sema Bektas,

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Neprilysin as a Biomarker

Noemi Pavo, Suriya Prausmüller, Philipp E Bartko, et al

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ST2 in Heart Failure With Preserved Ejection Fraction

Veronika Zach, Felix Lucas Bähr, Frank Edelmann,

Category icon
Nitrates as a Treatment of Acute Heart Failure

Mohammad S Alzahri, Anita Rohra , W Frank Peacock,

Category icon
Practical Applications for Single Pill Combinations in the Cardiovascular…

Ferdinando Iellamo, Karl Werdan, Krzysztof Narkiewicz, et al

Category icon
SSO2 Therapy in STEMI to Reduce Infarct Size

Steven Yakubov, Andreas Schäfer, Richard Schatz et al

Category icon
Biomarkers in Routine Heart Failure Clinical Care

Sunil K Nadar, Muhammad Mujtaba Shaikh,

Category icon
Biomarker Guided Therapy in Chronic Heart Failure

Hans-Peter Brunner-La Rocca, Sema Bektas,

Category icon
Natriuretic Peptides in Chronic Heart Failure

Hans-Peter Brunner-La Rocca, Sandra Sanders-van Wijk,

Category icon
Neprilysin as a Biomarker

Noemi Pavo, Suriya Prausmüller, Philipp E Bartko, et al

About

Acute coronary syndrome (ACS) is one of the most common health problems globally and a leading cause of death and signficiant morbidity in developed countries. It represents a clinical condition characterised by rapidly developing critical myocardial ischaemia. ACS encompasses three related but distinct clinical entities – unstable angina, non-ST-segment elevation MI (NSTEMI), and ST-segment elevation MI (STEMI).

Acute coronary syndromes are characterised by vascular inflammation, subsequent endothelial dysfunction and platelet activation, followed by thrombus formation. Uncontrolled thrombosis can culminate in complete vascular occlusion and STEMI.

Key diagnostic procedures for detection of patients with ACS are ECG at rest and markers of myocardial necrosis. Optical coherence tomography can be used to assess patients with ACS and is useful because it can detect plaques at high risk of rupture and provide additional information about plaque composition, thrombi and collagen. Troponin T and troponin I are specific cardiac markers for myocardial injury and diagnosing the myocardial necrosis.

Management of ACS should encompass both acute and long-term strategies.

What is Myocardial Infarction?

Also known as a heart attack, myocardial infarction (MI) is a necrosis of the heart muscle that originates from an acute obstruction of a coronary artery. It decreases blood flow and leads to irreversible damage to the heart due to myocardial ischaemia.

Related Articles

Articles

Natriuretic Peptides in Chronic Heart Failure

Hans-Peter Brunner-La Rocca, Sandra Sanders-van Wijk,

Published:

Citation: Cardiac Failure Review 2019;5(1):44–9.

Biomarkers in Routine Heart Failure Clinical Care

Sunil K Nadar, Muhammad Mujtaba Shaikh,

Published:

Citation: Cardiac Failure Review 2019;5(1):50–6.

Practical Applications for Single Pill Combinations in the Cardiovascular…

Ferdinando Iellamo, Karl Werdan, Krzysztof Narkiewicz,

Citation: Cardiac Failure Review 2017;3(1):40–5.

A Clinical Perspective on CNPs in Cardiac Failure

Noel S Lee, Lori B Daniels,

Citation: Cardiac Failure Review 2016;2(1):14–9