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View from the Thoraxcenter: ACC.22 Late-breaking Science Wrap-Up

Published: 14 Apr 2022

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Learn about the key take-home messages from ACC.22 with View from the Thoraxcenter hosts, Professor Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcenter, Erasmus MC, Rotterdam, NL).

In this succinct review video, they summarise the top late-breaking science trials and share their take on how the new data can be translated into practice.

Trials covered in detail include:

00:29: PACMAN AMI: Effects of Alirocumab on Coronary Atherosclerosis Assessed by Serial Multimodality Intracoronary Imaging in Patients with Acute Myocardial Infarction: A Double-blind, Placebo-controlled, Randomized Trial

03:48: VALOR-HCM: Mavacamten as an Alternative to Surgical Septal Myectomy or Alcohol Ablation in Patients with Severely Symptomatic Obstructive Hypertrophic Cardiomyopathy

05:42: Results of the EDIT-CMD Randomized Clinical Trial: Efficacy of Diltiazem to Improve Coronary Vasomotor Dysfunction in Angina and Nonobstructive Coronary Arteries

08:13: PROMPT-HF: A Cluster-Randomized PRagmatic Trial Aimed at ImprOving Use of Guideline Directed Medical Therapy in OutPatienTs with Heart Failure

10:12: The FAME 3 Trial: Quality of Life After Fractional Flow Reserve-guided Stenting Compared with Coronary Bypass Surgery

12:53: The FLAVOUR Randomized Clinical Trial: Comparison of Fractional Flow Reserve-guided and Intravascular Ultrasound-guided Percutaneous Coronary Intervention in Intermediate Coronary Artery Stenosis

17:47: Results From the PARTITA Trial: Catheter Ablation of Ventricular Tachycardia After the First Implantable Cardioverter Shock

19:38: Insights From the Corevalve US Pivotal and SURTAVI Trials: Five-year Incidence, Timing and Predictors of Hemodynamic Valve Deterioration of Transcatheter and Surgical Aortic Bioprostheses

22:37: A Randomized ADAPT-TAVR Trial: Edoxaban Versus Dual Antiplatelet Therapy For Valve Thrombosis and Cerebral Thromboembolism After Transcatheter Aortic-valve Replacement

25:08: 3-year Efficacy Outcomes From the Spyral Htn-on Med Pilot Study: Long Term Effect of Renal Denervation On Blood Pressure Reduction in Patients on Antihypertension Medications