ESC-HFA 2023: Late-Breaking Science Video Collection

Published: 23 May 2023

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Get the most out of the new data from, Late-breaker host, Dr Harriette Van Spall and Dr James Januzzi wrap up of the most impactful trials and studies presented at Heart Failure 2023.

Delve into in-depth and critical discussions with Dr Van Spall in our thought-provoking Late-breaker Discussion series.

For concise and practical take-home messages for practice and cardiovascular research watch our 5-minute Expert Interviews conducted with investigators.

Watch our Behind the Heart Series to hear more from the personal perspectives of the investigators behind the top trials of HFA 2023. 

About the episode

We are joined onsite by Dr Niklas Dyrby Johansen (Herlev and Gentofte Hospital, DK) to discuss the late-breaking results of the NUDGE-FLU trial in a cohort of patients with cardiovascular disease (CVD), originally presented at HFA's 2023 scientific sessions in Prague. 

NUDGE-FLU is a prospective, randomized, open-label implementation trial that enrolled over 96,0000 patients across Denmark. The study population included individuals who were eligible for the influenza vaccine in the Danish health system, 18 years and above. Patients were randomized into 1 of 10 study arms - one of which was a control, with 9 intervention arms. In the intervention arm, e-mail 'nudges' were sent to patients, encouraging them to receive their influenza vaccine.

Interview Questions: 
1. What is the importance of the NUDGE-FLU Trial, in the context of heart failure prevention?
2. Tell us more about the study design and cohort of patients with CVD in NUDGE-FLU?
3. How were the effects of vaccination measured against CVD patients within the trial?
4. What is the data presented at HFA 23?
5. What is the clinical significance of this data, and how can this be implemented into day-to-day practice?
6. What are the next steps?

Faculty Biographies

Niklas Dyrby Johansen

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