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Author(s): Till Hauffe , Bernard Krüger , Dominique Bettex , et al Added: 3 years ago
Shock in cardio-surgical intensive care unit (ICU) patients is a serious condition associated with a high morbidity and mortality.1,2 Prompt identification of the underlying condition and timely therapeutic interventions are key to reverse the shock state and to improve the patients’ outcome. Hence, the management during the first 6 hours is of paramount importance. This time period is also… View more
Author(s): Vasiliki Bistola , Angelos Arfaras-Melainis , Eftihia Polyzogopoulou , et al Added: 3 years ago
Acute heart failure (AHF) is defined as the sudden presentation or sudden aggravation of signs and symptoms of heart failure, often requiring hospitalisation.1 It is a life-threatening condition, with in-hospital mortality ranging from 22% to 37% in severe cases of cardiogenic shock.2–4 Inotropes have been used in the management of patients with AHF for decades, especially for patients with… View more
Author(s): Zoltán Papp , Piergiuseppe Agostoni , Julian Alvarez , et al Added: 3 years ago
Origins of a Unique Cardiovascular Agent Before the 1980s, therapy to enhance cardiac contractility in heart failure (HF) substantially meant oral digitalis glycosides, supplemented by beta-adrenergic agonists such as dopamine or dobutamine (introduced in the middle of the 1970s) in acute situations.1 It was therefore a matter of some note when the US Food and Drug Administration approved a new… View more
Author(s): Federica Jiritano , Valeria Lo Coco , Matteo Matteucci , et al Added: 3 years ago
Cardiogenic shock (CS) is a circulatory failure as a consequence of left, right or biventricular dysfunction.1 It leads to critical end-organ hypoperfusion due to primary cardiac dysfunction.1 Therefore, CS is not only a cardiac disease but also a multiorgan dysfunction syndrome involving the entire circulatory system, often complicated by a systemic inflammatory response syndrome.2 The goals of… View more
Author(s): Sajad Shehab , Christopher S Hayward Added: 3 years ago
The use of left ventricular assist devices (LVADs) in patients with advanced heart failure is well established; they make up 90% of all implanted continuous flow ventricular assist devices (VADs).1 In advanced heart failure, they are superior to medical therapy alone,1 with improvements demonstrated in survival, quality of life and functional status in carefully selected patients.2,3 Although… View more