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Author(s):
Rafael de la Espriella
,
Gonzalo Núñez-Marín
,
Pau Codina
,
et al
Added:
5 months ago
Foreword
Author(s):
Andrew JS Coats
,
Giuseppe Rosano
Added:
3 years ago
Article
Author(s):
Anupam A Kumar
,
Lena E Tran
,
Aniket S Rali
,
et al
Added:
1 year ago
Author(s):
Yih-Kai Chan
,
Alice M David
,
Caitlyn Mainland
,
et al
Added:
3 years ago
Primarily due to significant treatment advancements to prevent previously fatal acute cardiac events, the burden of heart failure (HF), characterised by chronic symptoms, acute hospitalisations and premature mortality, continues to rise.1,2 Latest expert guidelines3,4 confirmed by meta-analyses5,6 support the application of multidisciplinary HF management programs to improve health outcomes…
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Author(s):
Sebastiaan HC Klaassen
,
Dirk J van Veldhuisen
,
Hans LA Nienhuis
,
et al
Added:
3 years ago
Heart failure with a preserved ejection fraction (HFpEF) comprises half of the heart failure population, and is associated with high morbidity and mortality. HFpEF is induced by multiple coexisting comorbidities, mostly of non-cardiac origin, leading to increased stiffness of the myocardial wall, diastolic dysfunction, elevated filling pressures and eventually to heart failure.1 The interplay…
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Author(s):
Emilia D’Elia
,
Michele Senni
Added:
3 years ago
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which has reached a pandemic level worldwide.1 Bergamo was the first western town affected by the COVID-19 pandemic and has the sad record of being the city with the highest number of COVID-19 cases and deaths, not only in the Lombardy region but also throughout Italy and the world. The first…
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Author(s):
Sigrid L Johannesen
,
Colin M Barker
,
Melissa M Levack
Added:
2 years ago
Author(s):
Muhammad Shahzeb Khan
,
Javed Butler
Added:
4 years ago
In 2008, the European Medicines Agency and US Food and Drug Administration (FDA) issued industry guidance stating that all future novel glucose-lowering agent trials must undergo routine cardiovascular risk evaluation either before approval or as a post-marketing commitment.1 This mandated that all cardiovascular endpoint committees prospectively adjudicate all major adverse cardiovascular events…
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Author(s):
Marko Kumric
,
Tina Ticinovic Kurir
,
Josko Bozic
,
et al
Added:
2 years ago
Author(s):
Mark IM Noble
Added:
3 years ago
The simplicity of the concept of contractility is illustrated in Figure 1, which is the case for a strip of muscle connected to a force transducer. If one records the force of a contraction, and then measures it again at a longer length, the force is found to be higher. If by making other interventions, such as increasing the calcium ion (Ca2+) concentration of the extracellular fluid, and the…
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