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Link Between Synovial and Myocardial Inflammation: Conceptual Framework to Explain the Pathogenesis of Heart Failure with Preserved Ejection Fraction in Patients with Systemic Rheumatic Diseases
Author(s): Milton Packer Added: 3 years ago
Patients with a broad range of systemic inflammatory rheumatic diseases (i.e. rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis and ankylosing spondylitis) are exceptionally prone to cardiovascular disorders, but previous work concerning the development of heart disease in these individuals has largely focused on the risk of MI. However, the most important cardiovascular… View more

Heart Failure
Paul F Dellaripa
Research Area(s) / Expertise: Job title: Associate Professor
Personal History Dr Paul F. Dellaripa is a Rheumatologist at the Brigham and Women’s Hospital and an Associate Professor of Medicine at Harvard Medical School. He is based in Boston, Massachusetts. Academic History In 1989, Dr Dellaripa was awarded his M.D. from the University of Connecticut School of Medicine. He completed his Internal Medicine Residency (1990 - 1992) and his… View more
Anne Grete Semb
Dr Anne Grete Semb is Leader of the Preventive Cardio-Rheuma Clinic at theDiakonhjemme Hospital, in Oslo, Norway. She has over 190 publications in peer-reviewed international journals, book chapters and conference abstracts. Dr Semb has been leader of multiple clinical trials, and is founder of the Norwegian Female Cardiologist Society. She is also a steering committee member of the A… View more
Neprilysin as a Biomarker: Challenges and Opportunities
Author(s): Noemi Pavo , Suriya Prausmüller , Philipp E Bartko , et al Added: 3 years ago
Neprilysin (NEP) was more or less unrecognised by the cardiovascular community until 2014 when the Prospective Comparison of ARNi With ACEi to Determine Impact on Global Mortality and Morbidity in Heart Failure (PARADIGM-HF) study reported impressive clinical benefits resulting from the combination of an angiotensin receptor blocker (ARB) with a neprilysin inhibitor (angiotensin receptor… View more

MI/ACS
Author(s): Gerard T Giblin , Laura Murphy , Garrick C Stewart , et al Added: 2 years ago

Imaging & Diagnostics
Author(s): Simon Stewart , Trine T Moholdt , Louise M Burrell , et al Added: 3 years ago
There is universal acknowledgement that climate change and extreme weather events pose an increasing threat to global health.1,2 Precisely how this will affect patterns of disease is open to conjecture. For example, while it is predicted that increasingly warmer temperatures and more intense heat waves will provoke more cardiovascular, respiratory and renal events, a corollary reduction in… View more

Heart Failure
Cardiopulmonary Ultrasonography for Severe Coronavirus Disease 2019 Patients in Prone Position
Author(s): Aniket S Rali , Sergio Trevino , Edward Yang , et al Added: 3 years ago
Dear Editor, Case Presentation A 50-year old female presented to the emergency department with a 6-day history of fever, progressively worsening cough and shortness of breath. The patient did not report any contact with anyone who had been recently unwell or had been travelling. Upon arrival to the emergency room, the patient was noted to be severely hypoxaemic by pulse oximetry (66%) and in… View more

Imaging & Diagnostics

COVID-19
Red Cell Volume Distribution Width as Another Biomarker
Author(s): Artemio García-Escobar , Juan Manuel Grande Ingelmo Added: 3 years ago
To the Editor, We congratulate Nadar and Shaikh for their excellent review of the use of biomarkers in heart failure (HF), as well as the new biomarkers currently under investigation.1 Red blood cell distribution width (RDW) is a measure of the heterogeneity of distribution of red blood cell size. A high RDW implies a large variation in red blood cell (RBC) size (anisocytosis) and a low RDW… View more

Heart Failure
Imaging in Women with Heart Failure: Sex-specific Characteristics and Current Challenges
Author(s): Isabella Leo , Eleni Nakou , Antonio de Marvao , et al Added: 1 year ago

Imaging & Diagnostics

Heart Failure
Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019-associated Acute Respiratory Distress Syndrome: An Initial US Experience at a High-volume Centre
Author(s): Yang Yang , Aniket S Rali , Christian Inchaustegui , et al Added: 3 years ago
Dear Editor, The use of extracorporeal membrane oxygenation (ECMO) as salvage therapy in the most severe cases of acute respiratory distress syndrome (ARDS) has been associated with reduced mortality, particularly at high-volume centres. We report a case series of seven patients with coronavirus disease 2019 (COVID-19)-associated ARDS treated with ECMO. In select COVID-19 patients suffering… View more

COVID-19