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Author(s): Gabriele Fragasso Added: 3 years ago
The development of heart failure is rarely dependent on primary alterations of cardiac metabolism. The majority of heart failure cases result from diseases of the cardiac muscle, most frequently ischaemic heart disease. However, whatever the cause of heart failure, the net result will be depletion of myocardial adenosine triphosphate (ATP), phosphocreatine and creatine kinase levels with… View more

Heart Failure
Author(s): Giuseppe Rosano , Cristiana Vitale Added: 3 years ago
Heart failure (HF) affects 1–2% of the population in developed countries and absorbs a significant amount of human and economic resources.1–3 It is a complex syndrome, characterised by a spectrum of symptoms and signs ranging from minimal loss of normal functional capacity to more severe symptoms refractory to medical therapy. It may be associated with different aetiologies and varying degrees of… View more

Heart Failure
EMPATROPISM FE: Effects of Empagliflozin on iron metabolism in non-diabetic
Author(s): Christiane Angermann Added: 2 years ago
Prof Christiane E Angermann (University Hospital of Würzburg, Würzburg, DE) discusses a substudy of the EMPATROPISM Randomized Trial. The trial found that Empagliflozin administration to nondiabetic HFrEF patients significantly improves LV volumes, LV mass, LV systolic function, functional capacity, and quality of life when compared with placebo. the substudy, presented at AHA 21, looks into the… View more

Heart Failure
Author(s): Yury Lopatin Added: 3 years ago
Heart failure is currently one of the leading causes of death and disability worldwide, which makes it a major public health problem.1,2 Traditionally, heart failure is considered a complex syndrome with several features, including abnormal myocardial function and excessive, continuous neurohumoral activation. In this context, the current optimal pharmacological treatment of heart failure focuses… View more

Heart Failure
Job title: Director of the Obesity, Metabolism & Nutrition Institute
Dr Lee Kaplan is Director of the Obesity, Metabolism & Nutrition Institute, founding director of the Weight Center at the Massachusetts General Hospital, and associate professor of medicine at Harvard Medical School. Dr Kaplan's clinical expertise is in the areas of obesity medicine, gastroenterology and liver disease. The author of more than 150 medical and scientific papers, he has a special… View more
Joerg Herrmann
Research Area(s) / Expertise:

Cardio-oncology

Atherosclerosis and Hyperlipidemia

 Job title: Director, Cardio-Oncology Clinic, Mayo Clinic, Rochester, US
Joerg Herrmann, M.D., is a cardiologist researching how cancer and heart disease interact. Dr. Herrmann's research focuses on cardio-oncology, which studies the potential negative effects of cancer treatments on the circulatory system. Additionally, Dr. Herrmann is very interested in vascular illnesses, particularly the formation of atherosclerotic plaques and their effects. His work also… View more
Job title: MD
Job title: MD