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Author(s):
Gabriele Fragasso
Added:
3 years ago
The development of heart failure is rarely dependent on primary alterations of cardiac metabolism. The majority of heart failure cases result from diseases of the cardiac muscle, most frequently ischaemic heart disease. However, whatever the cause of heart failure, the net result will be depletion of myocardial adenosine triphosphate (ATP), phosphocreatine and creatine kinase levels with…
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Author(s):
Giuseppe Rosano
,
Cristiana Vitale
Added:
3 years ago
Heart failure (HF) affects 1–2% of the population in developed countries and absorbs a significant amount of human and economic resources.1–3 It is a complex syndrome, characterised by a spectrum of symptoms and signs ranging from minimal loss of normal functional capacity to more severe symptoms refractory to medical therapy. It may be associated with different aetiologies and varying degrees of…
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Author(s):
Marco Bergonti
Added:
11 months ago
EHRA 23 - Dr Marco Bergonti (Istituto Cardiocentro Ticino, CH) to discuss the key takeaways from the ANTWOORD II Trial.
In this study, 605 heart failure patients undergoing atrial fibrillation ablation were enrolled to receive an ANTWERP Score, which aimed to predict LVEF recovery. 70% of patients were categorised as 'responders', patients identified as those who could benefit the most from AF…
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Author(s):
Ernest Spitzer
,
Ben Ren
,
Felix Zijlstra
,
et al
Added:
3 years ago
Left ventricular ejection fraction (LVEF) is the most widely used parameter of left ventricular (LV) systolic function, and its deterioration is associated with reduced survival rates.1 LVEF is expressed as a percent value, and calculated by dividing the stroke volume (enddiastolic volume minus end-systolic volume) by the end-diastolic volume and multiplying by 100; however, volume measurements…
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Author(s):
Josep L Melero-Ferrer
,
Raquel López-Vilella
,
Herminio Morillas-Climent
,
et al
Added:
3 years ago
Heart failure (HF) is an epidemic with an increasing prevalence and an absolute mortality rate of approximately 50 % within 5 years of diagnosis. Imaging plays a main role in HF diagnosis, assessment of aetiology and treatment guidance. This article reviews current HF applications for all the available non-invasive imaging modalities: echocardiography, cardiovascular magnetic resonance (CMR),…
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Author(s):
Jackson J Liang
,
David J Callans
Added:
3 years ago
As the population ages, the incidence of both AF and heart failure (HF) will continue to increase. By the year 2030, there will be an estimated >12 million patients with AF and >8 million patients with HF.1,2 A significant proportion of patients with HF have reduced (<50%) left ventricular ejection fraction (heart failure with reduced ejection fraction, HFrEF) and the coexistance of AF…
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Author(s):
Davide Margonato
,
Simone Mazzetti
,
Renata De Maria
,
et al
Added:
3 years ago
Heart failure (HF) is a complex syndrome caused by functional and structural abnormalities of the left ventricle (LV) resulting in a combination of typical signs and symptoms. Historically, HF has been classified according to LV ejection fraction (EF) as either HF with reduced EF (HFrEF; LVEF <40%) or HF with preserved EF (HFpEF; LVEF >50%).1,2 The 2016 European Society of Cardiology (ESC)…
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Author(s):
Erik H Van Iterson
Added:
3 years ago
The maximal exercise oxygen uptake (VO2 max) response physiologically reflects the clinical status of patients with low-output left heart failure (HF). The failure of VO2 max to rise above 12 ml/kg/min is a hallmark of deteriorated clinical status, impaired oxidative metabolic capacity and indicates advanced medical therapy is required to prolong life.1,2 The continuous-flow left ventricular…
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Author(s):
Michael Y Henein
,
Per Lindqvist
Added:
3 years ago
Diastole is an important period in the cardiac cycle when all heart components integrate together to secure optimum ventricular filling which determines the stroke volume pumped by the ventricle in the succeeding cycle. Three diastolic phases are well-recognised; early diastole, diastasis and late diastole ‘atrial systole’ (Figure 1). To describe the actual events happening in the ventricle the…
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Author(s):
John Pepper
Added:
3 years ago
The most common cause of heart failure with reduced ejection fraction (HFrEF) in the industrialised world is coronary heart disease.1 Patients with an ischaemic aetiology of left ventricular systolic dysfunction have significantly higher mortality rates than those with non-ischaemic aetiologies.2 This more aggressive course represents the convergence of ischaemic myocardial fibrosis and…
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