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Author(s): Erik H Van Iterson Added: 3 years ago
The maximal exercise oxygen uptake (VO2 max) response physiologically reflects the clinical status of patients with low-output left heart failure (HF). The failure of VO2 max to rise above 12 ml/kg/min is a hallmark of deteriorated clinical status, impaired oxidative metabolic capacity and indicates advanced medical therapy is required to prolong life.1,2 The continuous-flow left ventricular… View more
Author(s): Kiran K Mirza , Finn Gustafsson Added: 3 years ago
According to the third report from the International Society for Heart and Lung Transplantation (ISHLT) Mechanically Assisted Circulatory Support Registry, more than 15,500 left ventricular assist devices (LVADs) were implanted worldwide between 2013 and 2017.1 Originally, LVADs were exclusively implanted as part of a bridge to transplantation (BTT) strategy, but in recent years a large… View more
Author(s): Sajad Shehab , Christopher S Hayward Added: 3 years ago
The use of left ventricular assist devices (LVADs) in patients with advanced heart failure is well established; they make up 90% of all implanted continuous flow ventricular assist devices (VADs).1 In advanced heart failure, they are superior to medical therapy alone,1 with improvements demonstrated in survival, quality of life and functional status in carefully selected patients.2,3 Although… View more
Author(s): Edo Y Birati , Mariell Jessup Added: 3 years ago
Heart failure (HF) is a leading cause of morbidity and mortality worldwide, affecting 1–2% of the adult population in western countries with incidence of 5–10 per 1000 persons per year.1,2 It is estimated that the prevalence of HF will continue to increase as the population ages and, according to the American Heart Association (AHA), by the year 2030 the prevalence of HF in the US alone will rise… View more
Author(s): Syed Yaseen Naqvi , Ibrahim G Salama , Ayhan Yoruk , et al Added: 3 years ago
Heart failure is a progressive and fatal disease that affects more than 23 million people worldwide, and will affect more than 8 million people in the USA by 2030.1,2 Despite major advancements in medical and device treatments for heart failure in recent decades, the incidence of heart failure continues to rise. This epidemic has a major impact on patient quality of life, while imposing heavy… View more
Author(s): Mandeep Mehra Added: 1 year ago
ESC 22 - Dr Mandeep Mehra joins us to discuss the 5-year outcomes of the MOMENTUM-3 Study (NCT02224755), a trial that aimed to evaluate the safety and effectiveness of Abbott's HeartMate 3 Left Ventricular Assist System in patients with advanced refractory left ventricular heart failure. The study enrolled 1028 participants implanted with the HeartMate 3 device, who were then monitored over 5… View more
Job title: University Hospital Jena, Jena, Germany