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Author(s): Giuseppe Rosano , Ilaria Spoletini , Cristiana Vitale , et al Added: 3 years ago
Heart failure (HF) affects 1–2% of the population in developed countries and absorbs a significant amount of human and economic resources.1,2 HF is a complex syndrome characterised by a spectrum of symptoms and phenotypes: HF with preserved ejection fraction, HF with mid-range ejection fraction and HF with reduced ejection fraction (HFrEF).3 Differentiating patients according to left ventricular… View more
Author(s): Mitja Lainscak Added: 3 years ago
The renin–angiotensin–aldosterone system (RAAS) is an essential regulatory component of cardiovascular homeostasis that exerts its actions through hormones, angiotensin II and aldosterone, which regulate vascular tone and blood pressure by causing vasoconstriction and renal sodium and water retention.1 Abnormalities in cardiac function in heart failure (HF) activate the RAAS and sympathetic… View more
Author(s): Davide Stolfo , Gianluigi Savarese Added: 5 years ago
Heart failure (HF) is a major and growing public health problem with high morbidity, mortality and costs.1 Due to the ageing the population, the mean age of patients with HF is increasing and exceeds 70 years in most developed countries. HF prevalence rises with age and exceeds 10% in people over 80.2 Older patients are more frail and have a higher risk of cardiovascular events. They also have a… View more
Foreword

Article

Author(s): Andrew JS Coats , Giuseppe Rosano Added: 3 years ago
It is with great pleasure that we introduce to you to this issue of Cardiac Failure Review. In this issue, we focus on clinical practice research and observations in advanced heart failure, a topic of increasing interest to triallists, innovators and practising physicians alike. We know the prognosis and outlook remains poor for advanced heart failure, especially if the patient is unlikely… View more
Author(s): Stefan Anker , Giuseppe Rosano , Javier de Juan Bagudá , et al Added: 5 months ago
Translational Medicine Academy (TMA) in partnership with Radcliffe Cardiology were delighted to announce the return of e-SPACE Heart Failure 2023. A thoughtfully curated programme supported the exploration of how leading experts are implementing the new heart failure guidelines into clinical practice and showed the latest information on patient profiling in heart failure for tailoring… View more
Author(s): John GF Cleland Added: 1 year ago
Prof John Cleland (University of Glasgow & Glasgow Royal Infirmary, Glasgow, UK) joined us to talk about heart failure management highlights in 2022 including a new phenotype, HFsnEF; available and new treatment options; news on SGLT2is and more. Recorded at Heart Failure 2022, Madrid. Videographer: Tom Green Editor: Mirjam Boros View more
Author(s): David Pham , Justin L Grodin Added: 3 years ago
Introduction Advances in heart failure medical therapy over the past few decades have improved the prognosis of patients with this condition. Despite this, heart failure remains a significant burden to the medical system as the incidence of heart failure hospitalisation continues to rise.1 Diuretics have been a mainstay of therapy in heart failure to relieve congestion and improve symptoms… View more
Author(s): John JV McMurray , Yuhui Zhang , Giuseppe Rosano , et al Added: 1 year ago
e-SPACE Heart Failure 2022 was the third edition of the annual global online conference on heart failure. Bringing together thought-leaders from across the globe and broadcast over three time-zones – Asia, Europe, and the Americas – e-SPACE Heart Failure 2022 optimised geographical reach whilst delivering both global and regional insight. Course leadership Prof Stefan Anker (Charité Campus… View more
Foreword

Article

Author(s): Andrew JS Coats , Giuseppe Rosano Added: 3 years ago
It is with great pleasure that we introduce to you, our readers, to volume 5, issue 2 of Cardiac Failure Review. This issue we are focusing on clinical syndromes and the impact and therapy of selected comorbidities commonly seen in the heart failure (HF) patient. Stolfo and Savarese take another look at the landmark trials of angiotensin-converting enzyme (ACE) inhibitors in HF from the… View more