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Author(s): Ovidiu Chioncel , Sean P Collins , Stephen J Greene , et al Added: 3 years ago
Hospitalisation is a critical event in the clinical course of heart failure (HF) and despite relatively rapid relief of symptoms, hospitalisation is followed by an increased risk of death and re-hospitalisation.1 While performance measures have been developed in the last few years with the intent of improving post-discharge outcomes, post-discharge mortality rates remain unchanged or have… View more
Author(s): Ali Valika , Maria Rosa Costanzo Added: 3 years ago
Sleep-disordered breathing (SDB) is common in heart failure (HF) patients and is associated with increased morbidity and mortality. Abnormal sleep patterns are often characterised by cycles of significant pauses in breathing and partial neurological arousals that lead to maladaptive neurohormonal activation. SDB is broadly classified into two types: obstructive sleep apnea (OSA) and central sleep… View more
Author(s): John Pepper Added: 3 years ago
The most common cause of heart failure with reduced ejection fraction (HFrEF) in the industrialised world is coronary heart disease.1 Patients with an ischaemic aetiology of left ventricular systolic dysfunction have significantly higher mortality rates than those with non-ischaemic aetiologies.2 This more aggressive course represents the convergence of ischaemic myocardial fibrosis and… View more
Author(s): Piergiuseppe Agostoni , Dimitrios T Farmakis , Jose M García-Pinilla , et al Added: 3 years ago
The use of IV vasoactive drugs, diuretics, vasodilators and inotropes for correcting haemodynamic dysfunction in patients with decompensated heart failure has been described over many decades.1 However, data on their effects on prognosis do not offer a convincing picture of clinical benefit.2 This is particularly true regarding IV inotropes. Clinical data collected on the effects of cardiac… View more