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Author(s): Katerina Fountoulaki , Nikolaos Dagres , Efstathios K Iliodromitis Added: 3 years ago
Heart failure (HF) is a feared endpoint for most cardiovascular diseases and is a major cause of morbidity and mortality. The worldwide prevalence of HF is between 2 and 3 % and rises sharply at around 75 years of age, so that the prevalence in 70- to 80-year-old people is between 10–20 %. With a 50 % 5-year survival rate, HF is predicted to be the leading cause of all morbidity by 2020.1,2… View more
Research Area(s) / Expertise:

Cardio-oncology

Heart Failure

Job title: Assistant Professor
Dr Giselle Melendez is anAssistant Professor atWake Forest University School of Medicine, Winston-Salem, US.Commencing her scientific career at the University of South Carolina School of Medicine, Dr. Melendez focused on molecular mediators of myocardial extracellular matrix remodeling and heart failure. Notably, her research uncovered vital insights into inflammatory cytokines TNF-α, IL-6, and… View more
Foreword

Article

Author(s): Andrew JS Coats , Giuseppe Rosano Added: 3 years ago
We have great pleasure in recommending this second issue of Cardiac Failure Review to our readers. We have a panel of exceptional experts who have reviewed topical issues varying from fundamental science underpinning the diseased heart muscle to practical advice on clinical management from the acute presentation and cardiogenic shock through to patient self-management. In this second issue we… View more
Author(s): Milton Packer Added: 3 years ago
Patients with a broad range of systemic inflammatory rheumatic diseases (i.e. rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis and ankylosing spondylitis) are exceptionally prone to cardiovascular disorders, but previous work concerning the development of heart disease in these individuals has largely focused on the risk of MI. However, the most important cardiovascular… View more
Author(s): Sebastian Rosch , Karl-Philipp Rommel , Markus Scholz , et al Added: 3 years ago
Heart failure with preserved ejection fraction (HFpEF) is a common disease with rapidly increasing incidence and prevalence due to demographic changes.1 Well-known risk factors, such as metabolic syndrome (arterial hypertension, diabetes, obesity and dyslipidaemia), chronic kidney disease and AF, predispose to the development of HFpEF, especially in older people. Establishing the clinical… View more
Author(s): Veronika Zach , Felix Lucas Bähr , Frank Edelmann Added: 4 years ago
Heart failure (HF) is a chronic, progressive disease with steadily increasing incidence rates and high morbidity and mortality that represents a major challenge in healthcare worldwide.1–3 The disease is characterised by chronic exacerbations, recurrent hospitalisations and poor prognosis.1,2 Survival rates in HF patients are lower than in patients suffering from some malignant diseases,… View more