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Effects of GLP-1 Receptor Agonists in Heart Failure Patients
Author(s): Anastasia Shchendrygina , Amina Rakisheva , Ilya Giverts , et al Added: 1 year ago

Heart Failure
HFSA 24: STEP-HFpEF: Exercise Function and Frailty Status
Author(s): Mikhail Kosiborod Added: 1 year ago
HFSA 24 - We are joined virtually by Dr Mikhail Kosiborod (Saint Luke’s Mid America Heart Institute, US) to discuss findings from the STEP-HFpEF trial programme in regard to the efficacy of semaglutide according to frailty status, and exercise function at baseline.Interview Questions:1. Could you remind us of the importance of STEP-HFpEF2. What was the study design and patient population?3. What… View more

Prevention & Chronic Conditions

Cardiovascular Kidney Metabolic
HFSA 25: Excercise Effects of Aficamten Vs Metoprolol in MAPLE-HCM
Author(s): Gregory Lewis Added: 6 months ago
HFSA 25 - Aficamten improves excercise capacity compared to metoprolol in patients with obstructive hypertrophic cardiomyopathy in a prespecified analysis of the MAPLE-HCM study.Dr Gregory Lewis joins us to discuss findings from a prespecified cardiopulmonary exercise testing analysis of the MAPLE-HCM trial, which reveals divergent effects between aficamten and metoprolol on exercise performance… View more

Heart Failure
Klaus Witte
Klaus Witte is a Cardiologist at the Leeds Institute of Cardiovascular & Metabolic Medicine, Leeds, UK, where his research group focuses on patient-orientated questions with a commitment to enhancing efficacy through the personalised application of new and existing therapies in chronic heart failure (CHF).Challenging conventional teaching around heart rate and exercise capacity in CHF, Dr Witte’s… View more
Optimized Pacing Eases oHCM Symptoms in EMORI-HCM Trial
Added: 3 months ago Source:  Radcliffe Cardiology
For patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM), the net effect of right ventricular pacing (RVP) has been variable, as it can reduce the left ventricular outflow tract gradient (LVOTg) but may also decrease cardiac output.¹ The EMORI-HCM trial investigated whether electromechanically optimising the atrio-ventricular delay (AVD) could allow RVP to achieve a consistent… View more

Electrophysiology & Arrhythmia

Heart Failure
The Role of GLP-1 in Heart Failure
Author(s): Amina Rakisheva , Anton Zatsarinnyy Added: 3 months ago

Inherited and Congenital Cardiac Conditions

Heart Failure
THT 2025: The SUMMIT Trial
Author(s): Barry Borlaug Added: 1 year ago
THT Conference 2025 - Outcomes assessing the effect of obesity severity on tirzepatide in patients with obesity-related heart failure with preserved ejection fraction (HFpEF) show that patients on tirzepatide with a greater reduction in BMI and baseline waist-to-height ratio had greater improvements in exercise capacity and KCCQ quality of life scores.Dr Barry Borlaug (Mayo Clinic and Foundation,… View more

Prevention & Chronic Conditions

Cardiovascular Kidney Metabolic
AHA 24: The ENDEAVOR Trial
Author(s): Added: 1 year ago
AHA Conference 2024 - Primary safety and efficacy results from ENDEAVOR investigating the effect of myeloperoxidase inhibition with mitiperstat (AstraZeneca) on symptoms and exercise capacity in patients with heart failure with preserved or mildly reduced ejection fraction (HFpEF/HFmrEF).Dr Sanjiv Shah (Bluhm Cardiovascular Institute, Chicago, US) joins us onsite at AHA Conference to discuss the… View more

Heart Failure
Iron Deficiency in LVAD Patients
Author(s): William Herrik Nielsen , Finn Gustafsson Added: 1 year ago

Heart Failure
ESC 25: EMORI-HCM: Electromagnetically Optimised Right Ventricular Pacing for oHCM
Author(s): Ahran D Arnold Added: 8 months ago
ESC Congress 2025 - EMORI-HCM finds that right ventricular pacing (iRVP) improves symptoms in obstructive hypertrophic cardiomyopathy (oHCM) patients.Dr Ahran Arnold (Imperial College London, UK) discusses findings from the EMORI-HCM study, exploring electro-mechanically optimised right ventricular pacing as a novel therapeutic approach for patients with oHCM.This interventional trial examined… View more

Intervention

Electrophysiology & Arrhythmia