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Author(s):
Mark IM Noble
Added:
3 years ago
The simplicity of the concept of contractility is illustrated in Figure 1, which is the case for a strip of muscle connected to a force transducer. If one records the force of a contraction, and then measures it again at a longer length, the force is found to be higher. If by making other interventions, such as increasing the calcium ion (Ca2+) concentration of the extracellular fluid, and the…
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Author(s):
Martin Nicol
,
Mathilde Baudet
,
Alain Cohen-Solal
Added:
3 years ago
Advances in the early detection and treatment of cancer have improved overall survival in cancer patients. Nevertheless, cardiovascular diseases appear as the major cause of morbidity and mortality among cancer survivors.1 Left ventricular (LV) dysfunction and/or heart failure are the most common cardiovascular complications after administration of chemotherapies. The term ‘cardiotoxicity’ is…
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Author(s):
Ernest Spitzer
,
Ben Ren
,
Felix Zijlstra
,
et al
Added:
3 years ago
Left ventricular ejection fraction (LVEF) is the most widely used parameter of left ventricular (LV) systolic function, and its deterioration is associated with reduced survival rates.1 LVEF is expressed as a percent value, and calculated by dividing the stroke volume (enddiastolic volume minus end-systolic volume) by the end-diastolic volume and multiplying by 100; however, volume measurements…
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Exercise Training in HFpEF
Author(s):
Hidekatsu Fukuta
Added:
3 years ago
Article
Author(s):
Mary-Tiffany Oduah
,
Varun Sundaram
,
Yogesh Reddy
Added:
11 months ago
Author(s):
Conor P Kerley
Added:
3 years ago
Heart failure (HF) is a major cause of hospitalisation, morbidity and mortality. Nutritional factors are major contributors to HF precursors, including hypertension, obesity, dyslipidaemia, insulin resistance/diabetes and systemic inflammation. Multiple landmark trials, including Dietary Approaches to Stop Hypertension (DASH)1 and Prevención con Dieta Mediterránea (PREDIMED),2 have documented the…
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Author(s):
Ivan Milinkovic
,
Giuseppe Rosano
,
Yury Lopatin
,
et al
Added:
3 years ago
Chronic heart failure (HF), a complex and heterogeneous clinical syndrome, is a major cause of morbidity and mortality worldwide, and represents a major challenge to health care systems. The prevalence of HF and the number of hospitalisations is rising, even more in the ageing population.1 The direct costs of HF management reached 1–2 % of total health care expenditure and approximately two…
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Author(s):
Wesley J Tucker
,
Michael D Nelson
,
Rhys I Beaudry
,
et al
Added:
3 years ago
Heart failure (HF) is a major healthcare problem associated with high rates of morbidity and mortality.1 Approximately 6 million Americans aged ≥20 years have HF, and it is the leading cause of hospitalisation among older adults with estimated healthcare costs of US$31 billion annually.1,2 HF with preserved ejection fraction (HFpEF) accounts for over 50 % of all HF cases, and unlike HF with…
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Author(s):
Pieter Martens
Added:
2 years ago