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Author(s): Cristiana Vitale , Ilaria Spoletini , Giuseppe Rosano Added: 3 years ago
Exercise intolerance is a typical symptom of heart failure (HF), impairing patients’ ability to perform activities of daily living and affecting quality of life (QOL).1 Chronic HF is characterised by a progressive reduction in exercise capacity, increasing fatigue and shortness of breath.2 In addition, exercise intolerance is often accompanied by increased blood pressure and chronotropic… View more

Heart Failure
Biomarkers in Heart Failure with Preserved Ejection Fraction
Author(s): Antoni Bayés-Genís , Germán Cediel , Mar Domingo , et al Added: 1 year ago

Heart Failure
Heart Block Post-TAVR
Author(s): Anthony J Mazzella , Sameer Arora , Michael J Hendrickson , et al Added: 2 years ago

Electrophysiology & Arrhythmia
Author(s): John Pepper Added: 3 years ago
The most common cause of heart failure with reduced ejection fraction (HFrEF) in the industrialised world is coronary heart disease.1 Patients with an ischaemic aetiology of left ventricular systolic dysfunction have significantly higher mortality rates than those with non-ischaemic aetiologies.2 This more aggressive course represents the convergence of ischaemic myocardial fibrosis and… View more

Vascular Disease and Surgery

Heart Failure
Author(s): Sajad Shehab , Christopher S Hayward Added: 3 years ago
The use of left ventricular assist devices (LVADs) in patients with advanced heart failure is well established; they make up 90% of all implanted continuous flow ventricular assist devices (VADs).1 In advanced heart failure, they are superior to medical therapy alone,1 with improvements demonstrated in survival, quality of life and functional status in carefully selected patients.2,3 Although… View more

Heart Failure
Author(s): Justien Cornelis , Jonathan Myers , Hein Heidbuchel , et al Added: 3 years ago
A hallmark symptom of chronic heart failure (CHF) is exercise intolerance associated with early fatigue and/or dyspnoea with a minimal degree of exertion. It is also associated with a decline in capacity to perform activities of daily living and a diminished quality of life (QoL). Both patients with heart failure with reduced left ventricular ejection fraction (HFrEF) and those with heart failure… View more

Heart Failure
Congestion and Diuretic Resistance in Acute or Worsening Heart Failure
Author(s): Ingibjörg Kristjánsdóttir , Tonje Thorvaldsen , Lars H Lund Added: 3 years ago
From Acute Heart Failure Towards Worsening or De Novo Heart Failure The natural history of heart failure (HF) is characterised by disease progression and episodes of worsening HF and acute decompensation requiring outpatient treatment intensification, emergency department or in-hospital care. Acute HF (AHF), also known as acute decompensated HF, is defined as a progressive and sometimes rapid… View more

Heart Failure
Breaking the Cycle of HFpEF and AF
Author(s): Otilia Țica , Waseem Khamboo , Dipak Kotecha Added: 1 year ago

Heart Failure
The Impact of Frailty and Comorbidities on Heart Failure Outcomes
Author(s): Thomas Salmon , Hani Essa , Behnam Tajik , et al Added: 2 years ago

Heart Failure
Heart Failure With Mid-range or Recovered Ejection Fraction: Differential Determinants of Transition
Author(s): Davide Margonato , Simone Mazzetti , Renata De Maria , et al Added: 3 years ago
Heart failure (HF) is a complex syndrome caused by functional and structural abnormalities of the left ventricle (LV) resulting in a combination of typical signs and symptoms. Historically, HF has been classified according to LV ejection fraction (EF) as either HF with reduced EF (HFrEF; LVEF <40%) or HF with preserved EF (HFpEF; LVEF >50%).1,2 The 2016 European Society of Cardiology (ESC)… View more

Heart Failure