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AHA 25: HFpEF as an Adipose Tissue Disorder
Author(s): Milton Packer Added: 5 months ago
AHA Scientific Sessions 2025 - Dr Milton Packer (Baylor University Medical Center, US) joins us to discuss his novel unifying hypothesis that heart failure with preserved ejection fraction arises primarily from visceral adipose tissue dysfunction and altered adipokine signaling, rather than as a heterogeneous disorder driven by multiple comorbidities.Interview Questions:Can you explain the core… View more

Prevention & Chronic Conditions

Cardiovascular Renal Metabolic
Clinical Frailty Scale Predicts Mortality in Heart Failure
Added: 3 months ago Source:  Radcliffe Cardiology
Frailty is a common and significant factor associated with adverse outcomes in patients with heart failure, but the prognostic utility of simple assessment tools in contemporary practice remains an area of investigation. A new study using data from a large Japanese registry has found that the Clinical Frailty Scale (CFS) effectively captures both physical and cognitive decline and is an… View more

Prevention & Chronic Conditions

Demographic
Aficamten Superior to Metoprolol in oHCM: MAPLE-HCM
Added: 1 month ago Source:  CFR Journal Radcliffe Cardiology
A prespecified, secondary analysis of the MAPLE-HCM trial has shown that aficamten monotherapy provides superior and rapid benefits across multiple domains of disease burden compared with metoprolol in patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM).¹ Aficamten is a next-in-class cardiac myosin inhibitor (CMI) designed to reduce myocardial hypercontractility by decreasing… View more

Heart Failure
Jessica Spence
Jessica Spence is an anesthesiologist and ICU fellow who is completing a PhD under the supervision of Dr. PJ Devereaux. She is a perioperative research fellow at PHRI whose research program focusses on the cognitive and functional outcomes of cardiac and non-cardiac surgery. View more
Job title: Professor of Medicine and an Associate Director of the Clinical and Translational Research Center/Clinical and Translational Science Award (CTSA)
Job title: Assistant Professor of Medicine and Director of Clinical Hypertension Programs
Dr. Augusto Vicario
Augusto Vicario is Clinical Cardiologist, graduated in Buenos Aires University and postgraduate in the El Salvador University, was Past President of the Buenos Aires Society of Cardiology (Argentine Federation of Cardiology) and Director of the “Heart and Brain Study”, a National Register of Cognitive Status in hypertensive patients. Today, he is full member of the Argentine Federation of… View more
Alicia Morgans
Research Area(s) / Expertise:

Cardio-oncology

 Job title: Medical Director, Survivorship Program
A Genitourinary Medical Oncologist at the Dana-Farber Cancer Institute, Alicia Morgans serves as the Medical Director of the Survivorship Program. She is an experienced clinician and researcher with knowledge of patient-reported outcomes, clinical trials, and incorporating patient preferences and beliefs into therapeutic decision-making. Her studies have looked into the skeletal, cardiovascular,… View more
Portrait image of Mehak Dhande
Research Area(s) / Expertise:

Electrophysiology & Arrhythmia

 Job title: Faculty Clinical Instructor
Dr Dhande is an interventional cardiac electrophysiologist at University of Pittsburgh Medical Center, with a master's degree in clinical informatics and management from Stanford University School of Medicine. She is a physician scientist leading international studies to test patient facing applications of generative AI agents, in collaboration with Heart Rhythm Society. As an advisor and… View more
Dr Danny Dvir, serves as the Director of Interventional Cardiology at The Shaare Zedek Medical Center in Jerusalem. With a profound dedication to advancing cardiovascular medicine, his research interests span various domains, including Interventional Cardiology, Internal Medicine, Primary Care, Coronary Intervention, Transcatheter Valve Intervention, and Structural Heart Innovations. View more