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Levosimendan Efficacy and Safety: 20 years of SIMDAX in Clinical Use
Author(s): Zoltán Papp , Piergiuseppe Agostoni , Julian Alvarez , et al Added: 3 years ago
Origins of a Unique Cardiovascular Agent Before the 1980s, therapy to enhance cardiac contractility in heart failure (HF) substantially meant oral digitalis glycosides, supplemented by beta-adrenergic agonists such as dopamine or dobutamine (introduced in the middle of the 1970s) in acute situations.1 It was therefore a matter of some note when the US Food and Drug Administration approved a new… View more

Heart Failure
Author(s): Eilidh Hill , Jackie Taylor Added: 3 years ago
In developed countries, it is estimated that 1–2 % of the adult population has heart failure (HF), with the prevalence increasing to more than 10 % in those aged >70 years.1 Despite advances in therapies for heart failure with reduced ejection fraction (HFrEF), it remains a condition associated with significant morbidity and mortality, punctuated by episodes of unplanned hospitalisation.2 HF… View more

Heart Failure
Treating Acute Heart Failure with Chronic Obstructive Pulmonary Disease
Author(s): Jelena Celutkiene , Mindaugas Balčiūnas , Denis Kablučko , et al Added: 3 years ago
Heart failure (HF) and chronic obstructive pulmonary disease (COPD) comorbidity poses substantial diagnostic and therapeutic challenges in acute care settings. Outcomes of this comorbidity are worse than in either disease alone.1,2 A hospital diagnosis of COPD is an independent predictor of all-cause and non-cardiovascular mortality in HF patients,3–5 associated with decrease in use of evidence… View more

Vascular Disease and Surgery

Heart Failure
Aortic Pulsatility Index in Heart Failure
Author(s): Tania Deis , Kasper Rossing , Finn Gustafsson Added: 1 year ago

Heart Failure
Transitional Care to Reduce Readmission Rates
Author(s): Wan Xian Chan , Weiqin Lin , Raymond Ching Chiew Wong Added: 3 years ago
Southeast Asian nations are increasingly facing a higher burden of cardiovascular risk factors,1 which in turn correlate with a propensity towards cardiac-related diseases including heart failure (HF). In Singapore, HF is the most common cardiac cause of hospitalisation, accounting for 17 % of all cardiac admissions2 In 2015, public hospitals recorded in excess of 5,700 unique HF admissions.3 The… View more

Demographic

Heart Failure
CONFIRM-HF – Targeting for Improvement in Exercise Capacity in Heart Failure
Author(s): Piotr Ponikowski Added: 9 years ago

Heart Failure
Author(s): Darshan H Brahmbhatt , Martin R Cowie Added: 3 years ago
Heart failure (HF) is increasing in prevalence globally, and is associated with considerable ill health, healthcare costs and mortality. Prevalence increases steeply with age, and the average age of a person admitted to hospital with decompensation in developed countries such as the UK is in the high 70s.1 Comorbidity is the rule, with half of hospitalised patients having at least five… View more

Heart Failure

Digital Health
Author(s): Tonje Thorvaldsen , Lars H Lund Added: 3 years ago
Heart failure (HF) is associated with poor quality of life, high risk of death and is the leading cause of hospitalisation.1 With an ageing population and improved care for cardiovascular diseases, the prevalence of HF is increasing. Despite advances in HF therapies, 1–10% of the population with HF progress to an advanced stage of the disease.2,3 In the US, an estimated 250,000–300,000 patients… View more

Heart Failure
Neurohormonal Modulation in HFpEF
Author(s): Vincenzo Castiglione , Francesco Gentile , Nicolò Ghionzoli , et al Added: 10 months ago

Standards & Guidelines

Heart Failure
CA125 as a Biomarker in Heart Failure
Author(s): Marko Kumric , Tina Ticinovic Kurir , Josko Bozic , et al Added: 2 years ago

Heart Failure