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Author(s):
Ivan Milinkovic
,
Giuseppe Rosano
,
Yury Lopatin
,
et al
Added:
3 years ago
Chronic heart failure (HF), a complex and heterogeneous clinical syndrome, is a major cause of morbidity and mortality worldwide, and represents a major challenge to health care systems. The prevalence of HF and the number of hospitalisations is rising, even more in the ageing population.1 The direct costs of HF management reached 1–2 % of total health care expenditure and approximately two…
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Author(s):
Maurizio Volterrani
,
Ferdinando Iellamo
Added:
3 years ago
Chronic heart failure (CHF) is a progressive disorder characterised by elevated cardiac filling pressures, reduced cardiac output and decreased oxygen delivery to the tissues.1 Activation of the sympathetic nervous system (SNS), along with activation of the renin–angiotensin–aldosterone system (RAAS), plays a fundamental role in the pathophysiology of CHF syndrome.2–5 Early in the course of heart…
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Author(s):
Ferdinando Iellamo
,
Karl Werdan
,
Krzysztof Narkiewicz
,
et al
Added:
3 years ago
Cardiovascular disease (CVD) is the leading cause of death worldwide and it is predicted that its incidence will increase markedly, particularly in developed countries, despite the introduction of new drugs and devices. One of the factors accounting for the limited effectiveness of pharmacological therapy is poor adherence to treatment, particularly in elderly patients. The use of combinations of…
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Author(s):
Cristiana Vitale
,
Ilaria Spoletini
,
Giuseppe Rosano
Added:
3 years ago
Exercise intolerance is a typical symptom of heart failure (HF), impairing patients’ ability to perform activities of daily living and affecting quality of life (QOL).1 Chronic HF is characterised by a progressive reduction in exercise capacity, increasing fatigue and shortness of breath.2 In addition, exercise intolerance is often accompanied by increased blood pressure and chronotropic…
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Author(s):
Martin R Cowie
,
Michel Komajda
Added:
3 years ago
Advances in diagnosis and treatment have improved the outlook for the estimated 26 million patients with heart failure (HF) worldwide,1 but there remains a continuing need for further reduction in mortality and hospitalisation and the associated social and financial consequences of the disease. In a European study of outcomes after HF hospitalisation, 17 % of patients died within 12 months and 44…
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Michelle Kittleson
Research Area(s) / Expertise:
Job title: Cardiologist & Professor of Medicine
Author
Foreword
Author(s):
Andrew JS Coats
,
Giuseppe Rosano
Added:
3 years ago
Article
Author(s):
Attilio Iacovoni
,
Emilia D’Elia
,
Mauro Gori
,
et al
Added:
3 years ago
Heart failure (HF) is a pandemic, chronic degenerative disease estimated to affect 38 million people worldwide, a number expected to increase with the ageing of the population.1 As a syndrome, it is associated with high mortality and morbidity, and consistently requires increasing resources. HF is the most frequent cause of hospitalisation in patients aged over 65 years, and hospitalised patients…
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Author(s):
Bao Tran
,
Gregg C Fonarow
Added:
3 years ago
Heart failure (HF) remains a major public health problem resulting in substantial morbidity, mortality and healthcare expenditures globally. The European Society of Cardiology (ESC) 2012 Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure and the American College of Cardiology Foundation (ACCF)/American Heart Association (AHA) 2013 Guideline for the Management of Heart…
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Author(s):
Ivan Milinkovic
,
Marija Polovina
,
Andrew JS Coats
,
et al
Added:
1 year ago