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Author(s): Julio A Chirinos , Nancy Sweitzer Added: 3 years ago
Detailed phenotyping of ventricular–arterial coupling (VAC) and systemic arterial haemodynamics provide important insights into the pathophysiology of left ventricular (LV) energetics, remodelling and fibrosis, and systolic and diastolic dysfunction in various disease states including heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF).1… View more
Author(s): Nicolas M Van Mieghem , Joost Daemen Added: 5 months ago
What should you keep an eye out for at this year's AHA Scientific Sessions?Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcenter, Erasmus MC, NL) return with their 'View from the Thoraxcenter' preview to highlight late-breaking and featured science trials being presented at this year's AHA Scientific Sessions. Join this dynamic discussion on some of the most anticipated data releases.The… View more
Author(s): Nicolas M Van Mieghem , Joost Daemen Added: 1 week ago
Our recurring review series, View from the Thoraxcenter, hosted by Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcentre, Erasmus MC, Rotterdam, NL) offers a thorough examination of late-breaking and featured scientific findings, highlighting significant data.To delve deeper into the pivotal clinical trial data unveiled at ACC 24, Dr Harriette Van Spall (McMaster University, Hamilton, CA)… View more
Author(s): Mandeep Mehra Added: 1 year ago
ESC 22 - Dr Mandeep Mehra joins us to discuss the 5-year outcomes of the MOMENTUM-3 Study (NCT02224755), a trial that aimed to evaluate the safety and effectiveness of Abbott's HeartMate 3 Left Ventricular Assist System in patients with advanced refractory left ventricular heart failure. The study enrolled 1028 participants implanted with the HeartMate 3 device, who were then monitored over 5… View more
Research Area(s) / Expertise:

Coronary Interventions

Coronary Physiology

Job title: Consultant Cardiologist
Clinical Associate Professor Jonathan Yap is a Consultant with the Department of Cardiology at NHCS. His subspeciality interest is in interventional cardiology, pulmonary hypertension and structural heart disease including transcatheter aortic valve interventions (TAVI) for aortic stenosis. He spent a year in the United States performing his advanced fellowship in structural heart interventions… View more
Added: 1 year ago
In this interview, Dr Joanna Osmanska (University of Glasgow, UK) outlines the findings of the SUBCUT-HF I (NCT04846816)and the SQI 01-01 studies (NCT04384653). The studies, presented at Heart Failure 2022, demonstrated that the novel subcutaneous furosemide resulted in similar efficacy in terms of diuresis and natriuresis when compared to intravenous furosemide.In addition to this the… View more
Abiomed: Manufacturer of Impella®Percutaneous Ventricular Assist Device Abiomed, founded in 1981, is a global pioneer in healthcare technology, with a mission to recover hearts and save lives. From the World’s first total replacement heart pump to the World’s smallest heart pump, Abiomed has developed a family of ventricular assist devices (VAD), namely the Impella® platform of percutaneous… View more
Author(s): Edo Y Birati , Mariell Jessup Added: 3 years ago
Heart failure (HF) is a leading cause of morbidity and mortality worldwide, affecting 1–2% of the adult population in western countries with incidence of 5–10 per 1000 persons per year.1,2 It is estimated that the prevalence of HF will continue to increase as the population ages and, according to the American Heart Association (AHA), by the year 2030 the prevalence of HF in the US alone will rise… View more
Author(s): Sajad Shehab , Christopher S Hayward Added: 3 years ago
The use of left ventricular assist devices (LVADs) in patients with advanced heart failure is well established; they make up 90% of all implanted continuous flow ventricular assist devices (VADs).1 In advanced heart failure, they are superior to medical therapy alone,1 with improvements demonstrated in survival, quality of life and functional status in carefully selected patients.2,3 Although… View more