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Foreword

Article

Author(s): Andrew JS Coats , Giuseppe Rosano Added: 3 years ago
It is with great pleasure that we introduce to you to this issue of Cardiac Failure Review. In this issue, we focus on clinical practice research and observations in advanced heart failure, a topic of increasing interest to triallists, innovators and practising physicians alike. We know the prognosis and outlook remains poor for advanced heart failure, especially if the patient is unlikely… View more

Heart Failure
Disparities in Heart Failure Remote Monitoring
Author(s): Ioannis Mastoris , Ersilia M DeFilippis , Trejeeve Martyn , et al Added: 1 year ago

Heart Failure
Heart Failure With Mid-range or Recovered Ejection Fraction: Differential Determinants of Transition
Author(s): Davide Margonato , Simone Mazzetti , Renata De Maria , et al Added: 3 years ago
Heart failure (HF) is a complex syndrome caused by functional and structural abnormalities of the left ventricle (LV) resulting in a combination of typical signs and symptoms. Historically, HF has been classified according to LV ejection fraction (EF) as either HF with reduced EF (HFrEF; LVEF <40%) or HF with preserved EF (HFpEF; LVEF >50%).1,2 The 2016 European Society of Cardiology (ESC)… View more

Heart Failure
Heart Failure and Cardiac Rehabilitation
Author(s): David R Thompson , Chantal F Ski , Alexander M Clark , et al Added: 1 year ago

Vascular Disease and Surgery

Heart Failure
Global Public Health Burden of Heart Failure
Author(s): Gianluigi Savarese , Lars H Lund Added: 3 years ago
Heart failure (HF) is a complex clinical syndrome characterised by the reduced ability of the heart to pump and/or fill with blood.1,2 From a physiological point of view, HF can be defined as an inadequate cardiac output to meet metabolic demands or adequate cardiac output secondary to compensatory neurohormonal activation (generally manifesting as increased left ventricular filling pressure).2… View more

Standards & Guidelines

Heart Failure
Author(s): Hans-Peter Brunner-La Rocca , Sandra Sanders-van Wijk Added: 3 years ago
Natriuretic peptides (NPs) are well established in the diagnostic process of heart failure (HF). Low levels of NPs are particularly useful to exclude heart failure (HF). Numerous studies, predominantly in patients presenting with acute onset of symptoms suspected of HF, have convincingly shown the value of NPs in this regard. A meta-analysis published in 2015 clearly summarised the value of brain… View more

Heart Failure

MI/ACS
Cell Therapy in Heart Failure with Preserved Ejection Fraction
Author(s): Sabina Frljak , Gregor Poglajen , Bojan Vrtovec Added: 2 years ago

Heart Failure
Polypharmacy in Older People With Heart Failure
Author(s): Maria Stefil , Matthew Dixon , Jameela Bahar , et al Added: 1 year ago

Heart Failure
Author(s): Sam Hayman , John J Atherton Added: 3 years ago
Heart failure (HF) is associated with significant morbidity and mortality and confers a major economic burden.1 Large randomised controlled trials (RCTs) have demonstrated that inhibition of the renin–angiotensin– aldosterone and sympathetic nervous systems improve outcomes in patients with HF and a reduced left ventricular ejection fraction (HFrEF) (see Figure 1),2–9 with clinical guidelines… View more

Heart Failure
Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?
Author(s): Nicole Ebner , Stephan Von Haehling Added: 3 years ago
Iron is an essential trace element that is present in a number of molecular systems, and it is increasingly recognised as an important cofactor for a variety of cell systems.1 It has been acknowledged that iron plays an important role in oxygen transport, as well as in cell growth and proliferation. In recent years, more insight has been gained into iron physiology and the regulation of cellular… View more

Heart Failure