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Jun 10, 2015
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3 years ago
What is Heart Failure?
Heart failure (HF) is a diagnosis made on clinical grounds, requiring at its simplest only a clinical history and physical examination findings, although, of course, certain investigations can help, especially imaging to assess left ventricular (LV) mechanical function. Unlike cancer, or even myocardial infarction (MI), there is no pathological or biochemical test that is…
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3 years ago
Heart Failure
In developed countries, approximately 1–2 % of the adult population has heart failure (HF), and the prevalence of this cardiovascular disease increases with age.1,2 HF can occur in the presence or absence of reduced left ventricular ejection fraction (LVEF), known as HF with reduced ejection fraction (HF-rEF) and HF with preserved ejection fraction (HF-pEF), respectively. The most…
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3 years ago
Heart failure (HF) can be defined haemodynamically as any abnormality of cardiac structure or function resulting in a failure to deliver oxygen at a rate adequate for tissue requirements, despite normal filling pressures – or only at the expense of increased filling pressures.1 Around half of patients with HF have reduced left ventricle ejection fraction (LVEF; EF <40 %) at rest (HF-REF).2
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3 years ago
Acute heart failure (AHF) is a leading cause of hospitalisation in developed nations, responsible for 67,000 admissions a year in the UK alone, an incidence which is set to increase with an ageing population.1 The prognosis remains poor: in-hospital mortality ranges from 4–11 % and in those patients surviving to discharge 50 % will be re-admitted and one-third will die within 12 months.2–6 These…
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