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REDUCE-IT: CV Outcomes With Icosapent Ethyl by Baseline LDL-C
Author(s): Deepak L Bhatt Added: 3 months ago
In this insightful interview, Dr Deepak Bhatt (Mount Sinai Hospital, US) joins us to discuss findings from a post-hoc analysis of the REDUCE-IT trial, examining how icosapent ethyl affects cardiovascular outcomes across different baseline LDL-C levels.The study included 8,175 statin-treated patients with elevated cardiovascular risk and triglyceride levels between 135-499mg/dL. All participants… View more

Prevention & Chronic Conditions
Biomarkers for Early Detection and Prognosis of Heart Failure
Author(s): Moza A Alzaabi , Amin Abdelsalam , Majid Alhammadi , et al Added: 1 year ago

Heart Failure
AHA 24 Late-Breaking Discussion: REALIZE-K
Author(s): Harriette Van Spall , Mikhail Kosiborod Added: 7 months ago
AHA Conference 2024 — REALIZE-K: Impact of sodium zirconium cyclosilicate (SZC) on HFrEF patient's potassium levels whilst on spironolactone.Late-Breaker Host, Dr Harriette Van Spall (McMaster University, CA) is joined onsite by Dr Mikhail Kosiborod (Saint Luke's Mid America Heart Institute, US) to discuss the findings from the REALIZE-K Study (NCT04676646; AstraZeneca).REALIZE-K is a phase 4… View more

Heart Failure

Prevention & Chronic Conditions
HFA 24 Late-Breaker Discussion: Insights from the STEP-HFpEF
Author(s): Harriette Van Spall , Mikhail Kosiborod Added: 1 year ago
HFA 2024 — Late-breaker host, Dr Harriette Van Spall (McMaster University, CA) sat down with Dr Mikhail Kosiborod (Saint Luke’s Mid America Heart Institute, US) to discuss insights from the STEP-HFpEF programme.STEP HFpEF aimed to test the hypothesis that treatment with semaglutide can improve symptoms in patients with HFpEF and obesity. This discussion centers around the background of the… View more

Heart Failure

Prevention & Chronic Conditions
ESC HF 25: CRISPR in ATTR-CM: Hereditary vs Wild-Type
Author(s): Marianna Fontana Added: 1 month ago
ESC HF 25 - A study investigating CRISPR gene editing with nexiguran ziclumeran in ATTR cardiomyopathy demonstrated favourable safety and tolerability, with consistent reductions in serum TTR in both wild-type and variant disease.Prof Marianna Fontana (University College London, UK) joins us to discuss the key findings from a two-part, open-label, phase 1 study investigating the treatment effect,… View more

Heart Failure
Biomarkers for Congestion in Heart Failure
Author(s): Antonio Luca Maria Parlati , Cristina Madaudo , Vincenzo Nuzzi , et al Added: 4 months ago

Heart Failure
Carmine De Pasquale
Job title: Senior Lecturer, BMBS, PhD, FRACP
Dr De Pasquale has expertise in heart failure and echocardiography. He is also a Senior Lecturer at the Flinders University where he has ongoing research interests in heart failure both at the laboratory scientific level and clinical therapeutics level. Dr De Pasquale was the president of the Cardiac Society of Australia and New Zealand Heart Failure Council in 2007-8, he took over as the… View more
ESC HF 25: The TITRATE-HF Study
Author(s): Jasper J Brugts Added: 1 month ago
ESC HF 25 - TITRATE-HF shows 65% of patients with de novo heart failure receive guideline recommended medical therapy at 6 months in the Netherlands.Dr Jasper Brugts (Erasmus University Medical Centre, NL) joins us to discuss the outcomes from the TITRATE-HF study, which investigated adherence to the 2021 ESC guideline reccommendations for patients with heart failure with reduced ejecton fraction… View more

Guidelines & Statements

Heart Failure
ESC 23: The HEART-FID Study
Author(s): Robert Mentz Added: 1 year ago
ESC 2023 — Dr Robert Mentz (Duke University Medical Center, US) joins us to provide a succinct summary of the findings and key take-home messages from the HEART-FID study (NCT03037931). HEART-FID(American Regent, Inc.) aimed to determine the safety and efficacy of iron therapy using intravenous (IV) ferric carboxymaltose (FCM) as compared to a placebo in the treatment of patients with heart… View more

Heart Failure